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Blood Flow Monitoring in
Scientific Research

Monitoring blood flow dynamics can be useful in many research applications.

Examples of clinical and preclinical research conducted by users of our technology include:

Diagram illustrating pressure buildup in the eye leading to optic nerve damage in glaucoma, relevant to why optic nerve blood flow is impaired in glaucoma.

Optic Nerve Head
Blood Flow Changes in Glaucoma Research

Researchers have used the XyCAM CRE to investigate optic nerve head blood flow changes associated with glaucoma, a condition where blockage of the aqueous humor outflow leads to significant damage to the optic nerve and retinal ganglion cells.  

Surgeon utilizing a microscope with blood flow monitoring capabilities for surgical interventions.

Imaging Retinal Blood
Flow for Oculomics
and Systemic Diseases

Pulsatile XyCAM CRE data on optic nerve head blood flow and retinal blood flow can be used in oculomics research to assess vascular manifestations of systemic pathologies such as diabetes, cardiovascular risk, and cognitive impairment.

Surgeon utilizing a microscope with blood flow monitoring capabilities for surgical interventions.

Blood Flow Monitoring and Occlusion Status During  Surgical Interventions

Our blood flow monitoring technology has been modularly integrated with a surgical microscope and has demonstrated real-time noninvasive monitoring of blood flow in the field of view before, during, and after surgical interventions.   

Neonatal eye examination to assess changes in retinal blood flow and optic nerve head blood flow in prematurely born infants.

Imaging the Neonatal Eye for Clinical Research on Retinopathy of Prematurity

Researchers have used the XyCAM CRE mounted on an arm to image the eyes of prematurely born infants to assess retinal blood flow changes associated with retinopathy of prematurity, that poses a vision-threatening risk to the neonatal eye.

Illustration of the inside of a vessel with red blood cells flowing depicting the concept of blood flow.

Blood Flow Monitoring in Exposed Tissues for  Mechanistic Research

Our blood flow monitoring technology has been used in animal models to assess microvascular blood flow changes in stimulation-related neurophysiology experiments, wound healing angiogenesis experiments, and radiation response experiments. 

Illustration with a large question mark covered with blood vessels depicting the concept of yet uncontemplated applications of blood flow monitoring and assessment of blood vessel status.

How Can Our Blood Flow Monitoring Technology Support Your Research?

Our technology can image blood flow in any optically accessible tissue. Contact us to find out how we can help you obtain and analyze blood flow information for your current and future research applications. Contact us.

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