Scientific Reading
From our research teams
Clinical Research on Ocular Blood Flow
Cho E, Das U, Sidelnikov D, Balasubramanian T, Shats D, Mansoor S, Forbes H-E, Zhou J, Kapoor R, Chase S, Kore M, Williams K, Saeedi OJ, Sundararajan S, Levin MR, Magder L, Alexander JL (2024) “Retinal blood flow association with age and weight in infants at risk for retinopathy of prematurity”, Scientific Reports 14, art.12790.
Shats D, Balasubramanian T, Sidelnikov D, Das U, Onyekaba N-A., Forbes HE, Lu N, Williams K, Levin MR, Sundararajan S, Vij S, Gadagkar H, Rege A, Levin MR, Saeedi OJ, Chen V, Alexander JL (2023) “Association of Speckle-based Blood Flow Measurements and Fluorescein Angiography in Infants with Retinopathy of Prematurity”, Ophthalmology Science, vol. 4, no. 4, art. 100463.
Vinnett A, Kandukuri J, Le C, Cho K-A, Sinha A, Asanad S, Thompson G, Chen V, Rege A, Saeedi OJ (2021) “Dynamic Alterations in Blood Flow in Glaucoma Measured with Laser Speckle Contrast Imaging,” Ophthalmology Glaucoma, Oct 18, 2021, S2589-4196(21)00240-4.
DeBuc DC, Rege A, Smiddy WE (2021) “Use of XyCAM RI for Noninvasive Visualization and Analysis of Retinal Blood Flow Dynamics During Clinical Investigations,” Expert Review of Medical Devices, pp 1–13.
Marino M, Gehlbach PL, Rege A, Jiramongkolchai K (2021) “Current and novel multi-imaging modalities to assess retinal oxygenation and blood flow,” Eye 35 (11), pp 2962 - 2972, Epub June 11, 2021.
Cho K-A, Rege A, Jing Y, Chaurasia A, Guruprasad A, Arthur E, DeBuc DC (2020) “Portable noninvasive video-imaging of retinal blood flow dynamics,” Scientific Reports 10, art. 20236.
Rege A, Cunningham SI, Liu Y, Raje K, Kalarn S, Brooke MJ, Schocket L, Scott S, Shafi A, Toledo L, Saeedi OJ (2018), “Noninvasive assessment of retinal blood flow using a novel handheld laser speckle contrast imager,” Translational Vision Science and Technology 7 (6), art. 7.
Preclinical Imaging of Non-ophthalmic Tissue Blood Flow
Kandukuri J, Jain A, Karmarkar P, Gadagkar H, Aberman H, Wang Q, Rege A (2024) "Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study" Innovative Surgical Sciences, March 26, 2024.
Mangraviti A, Volpin F, Cha J, Cunningham SI, Raje K, Brooke MJ, Brem H, Olivi A, Huang J, Tyler BM, Rege A (2020) “Intraoperative laser speckle contrast imaging for real-time visualization of cerebral blood flow in cerebrovascular surgery: results from pre-clinical studies,” Scientific Reports 10, art. 7614.
Rege A, Seifert A, Schlattman D, Ouyang Y, Basaldella L, Li K, Tyler B, Brem H, Thakor NV (2012) “Longitudinal in vivo monitoring of rodent glioma models through thinned skull using laser speckle contrast imaging”, Journal of Biomedical Optics 17 (12), p. 126017.
Rege A, Thakor NV, Rhie K, Pathak AP (2012) “In vivo laser speckle contrast imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesis”, Angiogenesis, vol. 15, no. 1, pp. 87-98.
Li N, Jia X, Murari K, Parlapalli R, Rege A, Thakor NV (2009) "High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast," Journal of Neuroscience Methods 176, pp. 230-236.
Laser Speckle Contrast Imaging Technology
Senarathna J, Rege A, Li N and Thakor NV (2013) “Laser speckle contrast imaging: theory, instrumentation and applications”, IEEE Reviews on Biomedical Engineering 6, pp 99-110.
Rege A, Tyler BM, Brooke MJ, Murari K (2013) “A portable hardware implementation for temporal laser speckle imaging”, Proceedings of IEEE Conference on Biomed Circuits and Systems (BioCAS) Amsterdam, pp. 44-48.
Rege A, Senarathna J, Li N, Thakor NV (2012) “Anisotropic processing of laser speckle images improves spatiotemporal resolution”, IEEE Transactions on Biomedical Engineering 59 (5), pp. 1272-1280.
Rege A, Murari K, Seifert A, Pathak AP, Thakor NV (2011) "Multi exposure laser speckle contrast imaging of the angiogenic microenvironment," Journal of Biomedical Optics 16 (5), p. 056006.
Rege A, Murari K, Li N, Thakor NV (2010) "Imaging microvascular flow characteristics using laser speckle contrast imaging," in Proceedings of the 32nd Annual International Conference of IEEE Engineering in Medicine and Biology Society (EMBC), Buenos Aires, pp. 1978-1981.
Miao P, Rege A, Li N, Thakor NV, Tong S (2010) "High resolution cerebral blood flow imaging by registered laser speckle contrast analysis," IEEE Transactions in Biomedical Engineering 57, pp. 1152-1157.